… to a rewarding dose of cocaine (10 mg/kg) elevating the … induced cocaine seeking in rats
after extended withdrawal from … If this holds true, our findings are in agreement with a previous …

… the pre-test was the one that was paired with cocaine during the … , the relationship between
reward thresholds and cocaine self-… differences in cocaine-induced increases in locomotor …

… Cocaine conditioned place preference (CPP) experiments … the ratio of effort to reward to
measure cocaine-seeking, we … The observed increases in pre-synaptic sensitivity to cocaine …

… of the rewarding effects of cocaine in the conditioned place … during the pre and post
conditioning test. After each series of … Our results extend this regulation to other IEGs only in the …

… following day, they were injected with saline, given access to … 20-min access to water in the
test cages before being placed … and future assessments must extend the present analysis to …

… 30 infusions or for a 3 h time limit. For the final 6 d, the dosage of … (black) and cocaine-exposed
(gray) rats for each day of self-… Directly testing this issue has proven difficult in the past as …

… , rewarding and reinforcing effects of cocaine in adulthood. … an injection of cocaine or
MDPV immediately before being … mg/kg of cocaine or 2 mg/kg of MDPV once daily for four days…

… (CPP).32, 33 CPP is one useful model to study the rewarding … acclimate for at least 30 minutes
prior to handling or testing. … -induced reinstatement of cocaine self-administration,110 we …

… to extend social-enhanced methamphetamine reward reported … and cocaine, social and
methamphetamine rewards interact … 2 illustrates place preference before (baseline) and after (test…

… of cocaine were evaluated in the Conditioned Place … Natural place preference was determined
in a 15 min pre-test at … a weaker place preference following cocaine’s 7 day withdrawal …